Why did my weight loss plateau on GLP-1 peptides?

Weight loss plateaus are a normal physiological response during GLP-1 therapy. Research shows plateaus typically occur around 20 weeks with liraglutide and 60-68 weeks with semaglutide, as the body adapts through metabolic changes including reduced energy expenditure. Strategies to address plateaus include ensuring adequate protein intake, incorporating resistance training, and working with a healthcare provider to optimize dosing or consider dual-agonist options like tirzepatide.