Which peptides target stubborn belly fat and visceral fat?

Tesamorelin is the only FDA-approved peptide specifically for visceral fat reduction, approved for HIV-associated lipodystrophy. It is a synthetic GHRH analog that stimulates natural growth hormone release and has demonstrated approximately 18% visceral fat reduction in clinical studies while preserving lean mass. Other peptides studied for abdominal fat include AOD-9604 (growth hormone fragment targeting fat metabolism) and MOTS-c (mitochondrial peptide that activates AMPK). Most peptides for fat loss remain investigational and require medical supervision when used.