How long should you cycle on and off peptide stacks?

Most peptide stacks follow an 8-12 week on-cycle followed by a 4-6 week off-cycle to prevent receptor desensitization. A common approach is the 5-on/2-off weekly schedule within the active cycle, where you administer peptides for five days and rest for two. Growth hormone secretagogue stacks like CJC-1295 with Ipamorelin typically use 12 weeks on and 4 weeks off, while healing peptides like BPC-157 are often cycled for 4-8 weeks.