What is the best time to take sleep-related peptides?

Most sleep-related peptides like CJC-1295/Ipamorelin are optimally taken 20-30 minutes before bedtime on an empty stomach, ideally 2-3 hours after your last meal. This timing aligns with the bodys natural growth hormone release during deep sleep, which peaks between 10 PM and 2 AM. High insulin levels from recent food intake can blunt growth hormone release, reducing peptide effectiveness.