What are common injection site reactions from peptides and how can they be managed?

Common injection site reactions include temporary redness, swelling, itching, or tenderness at the injection location, which typically resolve within hours to days. These reactions often occur because the body initially perceives peptides as foreign substances, triggering a mild inflammatory response that usually diminishes with continued use. Rotating injection sites daily between the abdomen, upper thigh, and back of the upper arm helps prevent irritation, and using proper sterile technique reduces the risk of infection.