How does GHK-Cu peptide promote skin and tissue healing?

GHK-Cu is a naturally occurring copper-tripeptide that stimulates collagen synthesis, fibroblast proliferation, and angiogenesis (new blood vessel formation) at the wound site. Research published in PMC shows it can modulate over 4,000 human genes involved in tissue remodeling while increasing production of growth factors like VEGF and bFGF. Studies in animal models demonstrate improved wound contraction, faster granulation tissue development, and elevated antioxidant enzyme levels during the healing process.