Why is rotating injection sites important for peptide injections?

Rotating injection sites prevents lipohypertrophy, a condition where fatty tissue thickens or develops lumps from repeated needle trauma to the same area. Research shows lipohypertrophy affects over 50% of patients who inject regularly without proper rotation and can significantly impair drug absorption, making medication effects unpredictable. Move at least 1-2 cm from your previous injection spot and systematically rotate within your chosen anatomical region to allow tissue recovery time.