Should I take peptide injections before or after meals?

Most injectable peptides are best administered on an empty stomach, ideally 30-60 minutes before eating or 2-3 hours after your last meal. Food in the digestive system can reduce peptide bioavailability by up to 40% due to competitive absorption pathways and elevated insulin levels interfering with receptor binding. Growth hormone releasing peptides like Ipamorelin and Tesamorelin are particularly sensitive to meal timing, while GLP-1 medications such as semaglutide are not significantly affected by food intake.